|
March 8, 2023
6:00 pm Welcome Cocktail
March 9, 2023
9:00 am Opening Remarks
Session I
RKIP: General properties and role in diseases (I)
Chairmen: Kam Yeung; Stavroula Baritaki
9:30 am Plenary Lecture
Lessons from RKIP: Rewiring Signaling Pathways as
a Therapeutic Approach to Cancer
Marsha Rosner
9:55 am RKIP – a regulator of beta-adrenergic signaling in the heart
Kristina Lorenz
10:20 am RKIP as a CDK1 regulated inhibitor of the mitotic checkpoint
Christopher Figy
10:45 am Discussion
11:00 am Coffee break/Poster Session
Session II
YY1: General properties and role in diseases (I)
Chairmen: Benjamin Bonavida; Kathy Lui
11:30 am Plenary Lecture (online)
Phase separation regulates YY1-mediated enhancer formation in cancer cells
Guangchao Sui
11:55 am Balance of Yin Yang Family and Regulation of Cellular Redox Homeostasis
Vivi Kasim
12:20 am The importance of structural disorder in the molecular recognition of YY1 partners
Andrzej Gorecki
12:45 am Discussion
1:00 pm Light Lunch
Session III
RKIP: General properties and role in diseases (II)
Chairmen: Marsha Rosner; Gabor Balazsi
2:00 pm Effect of RKIP loss in mammary duct development and neoplastic transformation Kam Yeung
2:20 pm Synthetic biological investigation of the RKIP-BACH1 regulatory network
Gabor Balazsi
2:40 pm Usefulness of RKIP assessment in various cancer types: could it be a new reliable tumor marker?
Massimo Papale
3:00 pm Discussion
Session IV
YY1: General properties and role in diseases (II) Chairmen:Ferdinando Nicoletti; Joseph Kissil
3:15 pm YY1 in bone homeostasis and tumor angiogenesis Filomena de Nigris
3:35 pm YY1 as a moderator of stress-induced resistance of colorectal cancer cells
to immune-mediated cytotoxicity
Stavroula Baritaki
3:55 pm YY1 regulates Glucose Homeostasis Through Controlling Insulin Transcription in
Pancreatic β-Cells
Kathy Lui
4:15 pm Discussion
4:30 pm Closing Remarks
5:00 pm City tour - Sicilian Sea Food Dinner
March 10, 2023
Session V
RKIP: General properties and role in diseases (III)
Chairmen: Kristina Lorenz; Qais Al-Duwairi
9:00 am Plenary Lecture
GSK3 and RKIP in metabolic disorders: A proposal for a joint international
research program
Fahd Al-Mulla
9:25 am RKIP protects mitochondria under ischemic conditions
Theresa Brand
9:45 am Characterization of RKIP expression in different histological variants of leiomyoma
and in leiomyosarcoma
Ciarmela Pasquapina
10:05 am RKIP/PEBP1: Central to the Redox Loxsisome, Epithelial Biology and Asthma Sally Wenzel
10:25 am Effect of PHB ligands on RKIP expression and phosphorylation Laurent Desaubry
10:45 am Discussion
11:00 am Coffee break/Poster Session
Session VI
YY1: General properties and role in diseases (III)
Chairmen: Demetrios A. Spandidos; Benjamin Bonavida
11:15 am Different Role of Yin Yang 1 in Colon Cancer and B-cell NHL cells
Silvia Vivarelli
11:35 am Understanding the role of YY1 and YAP in neurofibromatosis type 2 (NF2)
Joseph Kissil
11:55 am Reprogramming effect of preimplantation embryonic microenvironment on cancer
stem cells and the role of Ying Yang 1
Oktem Gulperi
11:55 am Yin Yang 1 Phosphorylation Induces Vascular Endothelial Proliferation Promoting
Atherosclerosis Under Disturbed Flow
Jeng-Jiann Chiu
12:35 am Discussion
1:00 pm Light Lunch
Session VII
RKIP: General properties and role in diseases (IV)
Chairmen: Fahd Al-Mulla; Alexandre Ramos
2:00 pm RKIP and Lung Cancer: from the bench to bedside
Olga Martinho
2:20 pm Therapeutic effect of Novel chemical inhibitor for RKIP and TbetaR1
binding on NF2 syndrome
Bum-Joon Park
2:40 pm The role of RKIP in inflammation and tumor-immunity
Xiaojian Wang Hangzhou
3:00 pm A stochastic binary model for the regulation of gene expression
to investigate responses to gene therapy
Alexandre Ramos
3:20 pm Discussion
Session VIII
YY1/RKIP Cross talks
Chairmen: Apostolos Zaravinos; Gabor Balazsi
4:00 pm Cross-talks between RKIP and YY1: A multilevel pan-cancer analysis focusing on their expression, mutation, methylation, immune infiltration, and drug resistance Apostolos Zaravinos
4:20 pm RKIP and YY1 expression is modulated in tumour cells after repeated treatment with anticancer drugs inducing oxidative stress: implications for the development of tumour
resistance
Valentina Rapozzi
4:40 pm RKIP downregulation is associated with YY1 overexpression in lung cancer:
Diagnostic and Prognostic implication
Luca Falzone
5:00 pm Who is the winner? RKIP (David) or YY1 (Goliath) in fighting cancer
Benjamin Bonavida
5:25 pm Discussion
5:40-6:00 pm Closing Remarks
Arman Lari
7:00 pm Social Dinner
|
