SCIENZE DI BASE M - ZModule BIOLOGIA APPLICATA
Academic Year 2023/2024 - Teacher: DAVIDE BARBAGALLOExpected Learning Outcomes
The course aims to provide the information to understand the general principles on which life is based. The main objectives are the knowledge of the chemical and molecular basis of life, the study of the structures and functions of cells, the fundamental mechanisms of the transmission of genetic information, the principles of development and differentiation, and finally a general knowledge of the kingdoms of living beings.
The main knowledge acquired by the student will be
- the learning of the chemical and molecular bases of life, and the application of this knowledge to the study of the structure and functions of the prokaryotic and eukaryotic cell
- learning the basic mechanisms of duplication, transmission and expression of gene information
-the understanding of the fundamental mechanisms of development, differentiation and communication between cells.
-learning general notions about the Kingdoms of the living
- the development of the ability to communicate the information acquired through correct terminology
- the development of the ability to present the relevant information in a synthetic and clear way, by a logical and critical analysis.
Course Structure
The course is organized in 42 hours of frontal teaching through lectures with the aid of slides and videos
If the teaching is given in mixed or remote mode, some necessary changes could be introduced with respect to what was previously stated, in order to comply the program foreseen and reported in the syllabus.
Required Prerequisites
The student must have acquired the basic knowledge in the field of Biology provided by the normal high school curricula.
Attendance of Lessons
Detailed Course Content
Introduction to biology and methods of studying life. Origin of life and subdivision of the living. Prokaryotes and Eukaryotes. General information on the chemistry of living beings: carbohydrates and lipids, amino acids and proteins, nucleotides and nucleic acids. Eubacteria and Archaea. Origin of the eukaryotic cell: the animal and plant cell. Organelles of eukaryotes and biological entities of complex classification. Cell membranes and membrane transport. The eukaryotic nucleus and the structure of the eukaryotic chromosome. DNA structure and replication. Transmission of genetic information: the genetic code and transcription. Ribosomes, translation and protein synthesis. Control of gene expression: post-transcriptional and post-translational modifications. The cytoskeleton and intracellular communication. Cell cycle, mitosis and meiosis. Mitochondria and the mitochondrial genome. Communication between cells: signal transduction. Apoptosis. Stem cells. Basics of Mendelian genetics.
Textbook Information
Hillis et al., Fondamenti di Biologia - Zanichelli
Sadava et al., Elementi di Biologia e Genetica
De Leo et al., Biologia e Genetica - Edises
It is important to use last issue/edition of the indicated volumes.
Course Planning
| Subjects | Text References | |
|---|---|---|
| 1 | Biological molecules | Hillis et al., Savada et al. |
| 2 | Origin of the life and living being classification | Hillis et al., Savada et al. |
| 3 | Origin of Eukaryotes | Hillis et al., Savada et al. |
| 4 | Cell membranes and membrane transport | Hillis et al., Savada et al. |
| 5 | Nucleous and chromosomes | Hillis et al., Savada et al. |
| 6 | DNA structure and replication | Hillis et al., Savada et al. |
| 7 | RNA transcription and maturation | Hillis et al., Savada et al. |
| 8 | Ribosome, tRNA, and protein translation | Hillis et al., Savada et al. |
| 9 | Cytoskeleton and comunication inside the cell | Hillis et al., Savada et al. |
| 10 | Cell cycle, mitosis and meiosis | Hillis et al., Savada et al. |
| 11 | Mitochondria | Hillis et al., Savada et al. |
| 12 | Signal transduction | Hillis et al., Savada et al. |
| 13 | Apoptosis | Hillis et al., Savada et al. |
| 14 | Stem cells | Hillis et al., Savada et al. |
| 15 | Basics of mendelian genetics | Hillis et al., Savada et al. |
Learning Assessment
Learning Assessment Procedures
Verification of learning will take place through an oral exam.
Information for students with disabilities and / or SLD
To guarantee equal opportunities and in compliance with the laws in force, interested students can ask for a personal interview in order to plan any compensatory and / or dispensatory measures, based on the didactic objectives and specific needs. It is also possible to contact the CInAP contact person (Center for Active and Participatory Integration - Services for Disabilities and / or SLD) of the Department of Biomedical and Biotechnological Sciences.
Examples of frequently asked questions and / or exercises
Where do lysosomes originate from?
Which of the following molecules can act as a cell-to-cell signal receptor?
Under physiological conditions, how many chromosomes does a human cell have under diploidy conditions?