BIOMARCATORI LEGATI ALLA NUTRIZIONE

Module ISTOLOGIA

The aim of the teaching of the Histology discipline is to provide the student with the basic cytological and histological culture, also with computational supports, for the understanding of the general organization of higher cells, their specializations and interactions to perform specific functions of the tissues, essential for being able to practically recognize the morphological characteristics of cells and normal tissues of the human organism and the functional relationship with nutrition.

Frontal lessons.

If the teaching is given in a mixed or remote mode, the necessary changes may be introduced with respect to what was previously stated, in order to comply with the program envisaged and reported in the syllabus.

Obligation to attend

HUMAN HISTOLOGY

Study methods in cytology and histology: optical, electronic and bioinformatic microscopy techniques; preparation of tissues for microscopic examination; principles of histochemistry; principles of bioinformatics applied to tissue analysis.

EPITHELIAL TISSUES: Coating epithelia: General.

TROPHOCONNECTIVE AND SUPPORT TISSUES: Connective tissue proper: General; Cartilage tissue: Overview; Bone tissue: Overview

BLOOD: Plasma - Erythrocytes - Leukocytes: Neutrophil granulocytes, Eosinophilic granulocytes, Basophilic granulocytes, Lymphocytes, Monocyte / macrophage line - Monocytes - Platelets - Lymph - Hemopoiesis - General characteristics of the immune response - Cells and organs of the immune system - Natural immunity - Antibodies and antigens - Antigen recognition and presentation - Maturation and activation of T lymphocytes - Maturation and activation of B lymphocytes - Effector mechanisms of the cellular response - Effector mechanisms of the humoral response.

MUSCLE TISSUES: Generalities

NERVOUS TISSUE: Generalities

TISSUE-SPECIFIC DECONVOLUTION OF THE COMPOSITION OF IMMUNE CELLS: Analysis of gene expression, Biomedical and bioinformatics databases in the context of nutrition. Management of biological information. Main international organizations and databases. Extraction of associated information through links. Simple and complex queries. NCBI resources, The human protein Atlas, and EMBL-EBI. Transcriptomic deconvolution analysis in the context of inflammatory tissue processes in the context of nutrition.

HUMAN HISTOLOGY:

ELEMENTI DI ISTOLOGIA E CENNI DI EMBRIOLOGIA di S. Adamo, N. Bernerdini, C.Boitani, L. Bonsi, ……..… E. Ziparo - Piccin

Other teaching material: pdf documents uploaded on the STUDIUM digital platform, relating to the topics presented during the lectures.

Oral examination

The oral examination consists of an interview in which questions will be asked that will focus on the different topics of the study program.

The test allows to verify:

i) the level of knowledge of human histology in physiological conditions of the organism.

ii) clarity of presentation.

iii) the property of medical-scientific language.

For the attribution of the final grade, the following parameters will be taken into account:

Grade 29-30 with honors: the student has a thorough knowledge of the topics discussed during the exam; he is able to promptly and correctly integrate and critically analyze the topics covered by the interview; he has excellent communication skills and masters medical-scientific language.

Grade 26-28: the student has a good knowledge of the topics discussed during the exam, he is able to integrate and analyze the topics covered by the interview in a critical and linear way and he presents the topics clearly using an appropriate medical-scientific language;

Grade 22-25: the student has a fair knowledge of the topics discussed during the exam, even if limited to the main topics; he manages to integrate and analyze in a critical but not always linear way the topics covered by the interview and he exposes the topics quite clearly with a discrete property of language;

Score 18-21: the student has minimal knowledge of the topics discussed during the exam, he has a modest ability to integrate and critically analyze the topics covered by the interview and he explains the topics in a sufficiently clear way although the language property is underdeveloped;

Failed exam: the student does not have the minimum required knowledge of the main teaching contents. The ability to use specific language is very little or absent and he is unable to independently apply the acquired knowledge.

1 What is the morphological organization of the heart muscle?

2 What is the classification of the exocrine glands?

3 What are the functions of leukocytes?

4 What shape do erythrocytes have and why?

5 Describe the cytological characteristics of the neuron

6 Describe the structural differences between cartilage and bone tissue

7 What is the myelin sheath?

8 What is the ultrastructural organization of the skeletal muscle fiber?