MOLECULAR ONCOLOGY AND IMMUNOPATHOLOGY APPLIED TO HUMAN BIOTECHNOLOGY
Module ONCOLOGIA MOLECOLARE APPLICATA ALLE BIOTECNOLOGIE UMANE

Academic Year 2022/2023 - Teacher: Massimo LIBRA

Expected Learning Outcomes

The student must have developed theoretical, scientific and professional knowledge, specific skills and abilities necessary for understanding the molecular characteristics of the tumors underlying neoplastic transformation. Are specific areas of competence that the student must acquire the knowledge of clinical molecular methodologies in oncology (biopsy, liquid biopsy, tumor markers), genetic and epigenetic modifications underlying tumors and pharmacological and supportive therapies in oncology. Finally, the student must have gained direct experience in the most relevant laboratory diagnostic methods and in clinical trials.

Course Structure

The teaching will be in the front type and complemented by seminars. For the training of the student, the course materials will be distributed, including slides and scientific papers

Required Prerequisites

Molecular Biology, general biology and physiology

Detailed Course Content

1. Molecular epidemiology of tumors
2. Risk factors and etiological agents of neoplastic transformation
3. Epigenetics of tumors
4. Molecular alterations in tumors
5. Targeted therapy
6. Hereditary tumors
7. Immuno-therapy in tumors - Immune checkpoint inhibitor

Textbook Information

ROSA M. PASCALE - FRANCESCO FEO; Elementi di oncologia molecolare - Piccin

During the lessons, scientific publications and powerpoint presentations will be provided to the students to support the teaching activity

Course Planning

 SubjectsText References
11. Epidemiologia molecolare dei tumori
2 2. Fattori di rischio e agenti eziologici di trasformazione neoplastica
3 3. Epigenetica dei tumori
44. Alterazioni molecolari nei tumori
5 5. Targeted therapy
66. Tumori ereditari
77. Immuno-terapia nei tumori - Immune checkpoint inhibitor

Learning Assessment

Learning Assessment Procedures

Ora exam
VERSIONE IN ITALIANO