CELLULAR, MOLECULAR AND THERAPEUTIC TECHNOLOGIES - BIOLOGY, GENOMICS, HUMAN AND MEDICAL GENETICS
Module TECNOLOGIE TERAPEUTICHE

Academic Year 2022/2023 - Teacher: CLAUDIO BUCOLO

Expected Learning Outcomes

knowledge of the differences between traditional and biotechnological drugs; 

knowledge of the therapeutic use of medicines; knowledge of gene therapies; 

knowledge of cell therapies;

knowledge of the main methods for evaluating the pharmacological profile of biotechnological drugs. 

Ability to interpret scientific results in the research of biotechnological drugs.

Course Structure

lessons and exercises in classroom

Required Prerequisites

Required prerequisites: none
Attendance of lessons: compulsory
Exam test: no ongoing tests; no end-of-course test;
Exam dates: see calendar
Delivery of teaching material: handouts / slides Information for students with disabilities and / or SLD To guarantee equal opportunities and in compliance with the laws in force, interested students can ask for a personal interview in order to plan any compensatory and / or dispensatory measures, based on the didactic objectives and specific needs. It is also possible to contact the CInAP contact person (Center for Active and Participatory Integration - Services for Disabilities and / or SLD) of the Department of Biomedical and Biotechnological Sciences.

Attendance of Lessons

mandatory

Detailed Course Content

• Gene therapy

• Cell therapy

• Biological drugs in oncology

• Biological drugs in ophthalmology

• Biological drugs in dermatology

• Biological drugs in neurology

• Biological drugs for the cardiovascular system

• Notes on experimental models

• Notes on the validation of experimental data

• Notes on the correct interpretation of scientific data

Textbook Information

·      Goodman and Gilman - The pharmacological basis of therapeutics. McGraw Hill Ed.  13^ ed.




AuthorTitlePublisherYearISBN
Goodman and GilmanLe basi farmacologiche della terapiaZanichelli2000
Rossi, Cuomo, Riccardi Farmacologia. Principi di base e applicazioni terapeutiche.Minerva Medica2021

Course Planning

 SubjectsText References
1Gene therapyGoodman & Gilman's
2Cell therapyGoodman & Gilman's
3Biological drugs in oncologyGoodman & Gilman's
4Biological drugs in ophthalmologyGoodman & Gilman's
5Biological drugs in dermatologyGoodman & Gilman's
6Biological drugs in neurologyGoodman & Gilman's
7Biological drugs for the cardiovascular systemGoodman & Gilman's
8Notes on experimental modelsslides
9Notes on the validation of experimental dataslides
10Notes on the correct interpretation of scientific dataslides

Learning Assessment

Learning Assessment Procedures

oral examination on topics delivered during the lessons

Examples of frequently asked questions and / or exercises

Gene and cell-mediated therapy: eg. CAR-T, check point inhibitors, corneal stem cells · Biological drugs in oncology:
e. g.monoclonal antibodies, · Biological drugs in ophthalmology: eg. anti-VEGF drugs Biological drugs in dermatology: eg. monoclonal antibodies, fusion proteins · Biological drugs in neurology: eg. interferon-beta; natalizumab · Biological drugs for the cardiovascular system: eg. heparin
VERSIONE IN ITALIANO