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BIOCHIMICA GENERALE E BIOCHIMICA CLINICA APPLICATA ALLE BIOTECNOLOGIE M - Z
Module BIOCHIMICA CLINICA APPLICATA ALLE BIOTECNOLOGIE

Academic Year 2022/2023 - Teacher: VINCENZA BARRESI

Expected Learning Outcomes

The course is designed to provide students with a good foundation of knowledge in all aspects of Clinical Biochemistry. Introducing the fundamentals of instrumentation and methodology in the clinical chemistry and biochemistry laboratory medicine, lectures will cover urinalysis testing procedures and associated disease entities, as well as analysis of other body fluids. Clinical testing using automated and manual methods, measurement of pancreatic function and intestinal absorption, renal and liver function, enzymes, electrolytes, blood gases, lipids, toxicology, urinalysis, endocrinology, neurological, dysmetabolic, inflammatory and cardiovascular diseases.

Course Structure

Frontal teaching, Individual study.

Information for students with disabilities and / or SLD: To guarantee equal opportunities and in compliance with the laws in force, interested students can ask for a personal interview in order to plan any compensatory and / or dispensatory measures, based on the teaching objectives and specifications needs. It is also possible to contact the CInAP contact person (Center for Active and Participatory Integration - Services for Disabilities and / or SLD) of the Department of Biomedical and Biotechonological Sciences.

If the teaching is given in a mixed or remote way, the necessary changes may be introduced with respect to what was previously reported, in order to carry out the program reported in the syllabus.

Detailed Course Content

  1. The use of laboratory data in clinical practice
  2. The method of acquisition of laboratory data
  3. The interpretation of biochemical data
  4. Biochemistry of nutrition
  5. Assessment of liver function and diagnosis of jaundice
  6. Acute and chronic diseases of the liver
  7. Liver function and Hepatitis tests
  8. Diabetes mellitus
  9. Hypoglycemia
  10. Lipid metabolism, dyslipidemia and atherosclerosis
  11. Free radicals in the pathology
  12. Metabolism of ethanol and the pathology of alcoholism
  13. Complete blood count test
  14. Disorders of porphyrin and heme synthesis, hemoglobinopathies
  15. Plasma proteins and electrophoresis
  16. Blood groups and compatibility tests
  17. Hemostasis tests
  18. Kidney function tests and urine test
  19. Iperammoniemie
  20. Disorders in metabolism of amino acids (Phenylketonuria, Hyperhomocysteinemia);
  21. Disorders salt and water balance and acid-base balance;
  22. Disorders of purine metabolism (hyperuricemia, gout)
  23. Investigations on the cerebrospinal fluid
  24. Biochemical aspects of neurological diseases
  25. Metabolic effects of tumors and tumor markers
  26. Cellular aspects of clinical biochemistry and clinical molecular biology
  27. Molecular tests
  28. Clinical biochemistry in the diagnosis of acute pain in the chest and abdomen
  29. Biochemistry and molecular clinical biology of organ transplantation
  30. Notes on antiaging medicine

Textbook Information

  • Biochimica Clinica e Medicina di Laboratorio, Marcello Ciaccio e Giuseppe Lippi, Edises
  • Medicina di Laboratorio, G. Federici (Autore), – Mc GrawHill Medicina di laboratorio.
  • Medicina di Laboratorio. La diagnosi di malattia nel laboratorio clinico, M. Laposata (Autore) - Piccin
  • Medicina di Laboratorio. Logica e patologia clinica, I. Antonozzi, E. Gulletta (Autori) - Piccin
  • Medicina dell'Aging e dell'Antiaging. V. Calabrese et al. (Autori) - Edra
  • Nutrigenomica e Epigenetica. V. Calabrese et al. (Autori) - Edra

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