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PRINCIPI DI FISIOLOGIA E PATOLOGIA GENERALE APPLICATI ALLE BIOTECNOLOGIE A - L
Module PRINCIPI DI PATOLOGIA GENERALE

Academic Year 2022/2023 - Teacher: KATIA DOMENICA MANGANO

Expected Learning Outcomes

Know the causes of illness and their different nature: chemical, physical, biological (Etiology); know the different ways in which these causes bring damage to the organism (Pathogenesis); identify the organism's own defense mechanisms by studying the physiology of the Immune system and its functioning anomalies (Immunology and Immunopathology). The course will develop from the molecular level to higher grades of organization (cell, tissue, organ, apparatus, organism)

Course Structure

Frontal lesson

Should teaching be carried out in mixed mode or remotely, it may be necessary to introduce changes with respect to previous statements, in line with the programme planned and outlined in the syllabus.

Laboratory in presence mode

Required Prerequisites

As per the study manifesto

Attendance of Lessons

As per the study manifesto

Detailed Course Content

Frontal lesson

  • Introduction General Pathology
  • Alterations acid-base balance
  • Genetic diseases
  • Environmental pathology
  • Pathogenesis of bacterial and viral diseases
  • Cellular pathology: cellular adaptations (hyperplasia, hypertrophy, atrophy, metaplasia, dysplasia), apoptosis, necrosis
  • Regeneration, repair and healing
  • Inflammation: acute, chronic, inflammatory mediators
  • Fever and alterations of the temperature
  • Immune system: innate immunity, acquired (cell mediated and humoral)
  • Evasion of host defences
  • Primary and acquired immunodeficiencies (AIDS)
  • Hypersensitivity: I, II, III e IV type
  • Immune tolerance
  • Autoimmunity: pathogenetic mechanisms and some autoimmune diseases (multiple sclerosis, rheumatoid arthritis, type I diabetes)
  • Tumors
  • Atherosclerosis
  • Amyloidosis

Laboratory

Safety regulations in the pathology and immunology laboratory. Correct use of the reagents and the equipment supplied to the laboratory: precision balance, micropipettes, freezers, centrifuges, optical and inverted microscopes, incubators for cell culture and microbiology, autoclave, chemical and biological hoods. Application of immunological techniques (E.L.I.S.A., serum agglutination, protein and enzymatic assays, study of the in vitro activity of blood cells), basic techniques in molecular biology.

Textbook Information

  • Elementi di patologia generale per corsi di laurea in professioni sanitarie, Giovanni M. Pontieri – Piccin
  • Elementi di fisiopatologia GM Pontieri - Ed. Piccin

Learning Assessment

Learning Assessment Procedures

Oral examination

Verification of learning can also be carried out electronically, should the conditions require it

 Information for students with disabilities and/or SLD

To guarantee equal opportunities and in compliance with the laws in force, interested students can ask for a personal interview in order to plan any compensatory and/or dispensatory measures, based on the didactic objectives and specific needs. It is also possible to contact the CInAP contact person (Center for Active and Participatory Integration - Services for Disabilities and/or SLD) of the Department of Biomedical and Biotechnological Sciences.

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