APPLIED BIOCHEMISTRY

Academic Year 2022/2023 - Teacher: Daniele Filippo CONDORELLI

Expected Learning Outcomes

Knowledge on structure, function and regulation of biological macromolecules, metabolic pathways, mechanisms and regulation of enzymatic activities.

Course Structure

Classroom teaching.

Required Prerequisites

General chemistry, Organic Chemistry and General Biochemistry

Attendance of Lessons

As per University regulation

Detailed Course Content

1. Structure and function of organs and tissues at biochemical level;

2. Signal transduction systems described at the level of enzymatic activities and protein interactions;

3. Chemical and physical DNA damage and repair mechanisms

4. Biochemical techniques for separation, characterization and dosage of proteins, nucleic acids and metabolites.

Textbook Information

Fondamenti di Biochimica umana. M. Maccarrone. Zanichelli

Metodologie biochimiche e biomolecolari. M. Maccarrone. Zanichelli

ALTRO MATERIALE DIDATTICO

http://www.zammumultimedia.it/lez-1-informazioni-di-base-sul-dna.htm

http://www.zammumultimedia.it/lez-2-danno-al-dna-indotto-da-radiazioni-ultraviolette-uv.htm

fino a

http://www.zammumultimedia.it/lez-27-origine-delle-anomalie-genomiche-3.htm

Course Planning

	Subjects	Text References
1	DNA damage and repair	Corso MOOC del Prof. Condorelli su UNICT
2	Reactive species of oxygen, nitrogen and sulfur	cap. 2 Fondamenti di Biochimica umana
3	Hormones and bioactive lipids	cap. 3 Fondamenti di Biochimica umana
4	Blood biochemistry	cap. 9 Fondamenti di Biochimica umana
5	Liver Biochemistry	cap. 7 Fondamenti di Biochimica umana
6	Neurochemistry	cap 4 e 14 Fondamenti di Biochimica umana
7	Kidney biochemistry	cap. 8 Fondamenti di Biochimica umana
8	Heart biochemistry	cap. 6 Fondamenti di Biochimica umana
9	Muscle biochemistry	cap. 10 Fondamenti di Biochimica umana
10	Skin biochemistry	cap. 13 Fondamenti di Biochimica umana
11	Cancer biochemistry	cap.15 Fondamenti di Biochimica umana
12	Biochemistry and metals	cap. 17 Fondamenti di Biochimica umana
13	Biochemical methodology	cap. 5,6,7,8,10 Metodologie biochimiche e biomolecolari.

Learning Assessment

Learning Assessment Procedures

Oral exam.

Learning assessment may also be carried out on line, should the conditions require it.

Examples of frequently asked questions and / or exercises

Biochemistry of nervous system; liver biochemistry; carbohydrate and lipid metabolism: functional meaning, hormonal regulation and metabolic interrelationships.

VERSIONE IN ITALIANO

Corso di laurea magistrale in

Biotecnologie mediche