PHARMACOLOGY OF BIOTECHNOLOGICAL PRODUCTS
Academic Year 2023/2024 - Teacher: Mariangela CHISARIExpected Learning Outcomes
Students will learn the fundamental mechanisms that regulate the mechanism of action of biological drugs, their pharmacokinetics and studies for their authorization process to market. Also, students will learn about techniques used for the development of biotechnological products and clinical applications of some classes of these drugs. Students will learn how to approach to scientific experiments and how interpret results.
Course Structure
Traditional classes. Students are invited to actively participate with questions and comments on discussed topics.
Required Prerequisites
Basic knowledge in the following topics: Anatomy, Histology, Biochemistry, Physiology, Pathology
Attendance of Lessons
Mandatory attendance to classes, except for new instructions for contingent reasons
Detailed Course Content
Identification of molecular targets for biological drugs (b. d.)
B. d. production
B.d. Pharmacokinetics
Preclinical and clinical drug development
Biosimilar drugs
Experimental procedures
How to obtain and validate scientific data
Data interpretation from scientific articles
Textbook Information
- Rossi F., Cuomo V., Riccardi, C, "Farmacologia. Principi di base e applicazioni terapeutiche", Minerva Medica.
- Goodman e Gilman: "Le basi Farmacologiche della terapia. il Manuale" ed italiana; McGraw-Hill.
Course Planning
Subjects | Text References | |
---|---|---|
1 | Identification of molecular targets for biological drugs (b. d.) | see textbook tab |
2 | B. d. production | see textbook tab |
3 | B.d. Pharmacokinetics | see textbook tab |
4 | Preclinical and clinical drug development | see textbook tab |
5 | Biosimilar drugs | see textbook tab |
6 | Experimental procedures | see textbook tab |
7 | How to obtain and validate scientific data | see textbook tab |
8 | Data interpretation from scientific articles | see textbook tab |
Learning Assessment
Learning Assessment Procedures
Oral exam about topics listed in the program and discussed during classes. The final evaluation will be determined by appropriate use of the scientific language, the ability to explain what has been learned, as well as by the skills of critical thinking.
Examples of frequently asked questions and / or exercises
Receptor: types and functions, drug elimination, side effects and adverse reactions of bevacizumab, VEGF inhibitors
VERSIONE IN ITALIANO