Bio-physical and molecular basis

Module Applied biology

Knowledge of cell structure and functions. From cells to organisms. Basic molecular mechanisms involved in DNA duplication, regulation of gene expression, development, differentiation, cell proliferation, biogenesis of organelles and cellular structures, interaction between cells and evolution.

The course includes frontal lessons. Due to the COVID-19 emergency there may be variations to what was declared

Introduction to the Cell. The Universal Features of Cells on Earth. The Diversity of Genomes and the Tree of Life. The Chemical Components of a Cell. Catalysis and the Use of Energy by Cells. How Cells Obtain Energy from Food. The Shape and Structure of Proteins. Protein Function. The Structure and Function of DNA. Chromosomal DNA and Its Packaging in the Chromatin Fiber. The Global Structure of Chromosomes. DNA Replication Mechanisms. From DNA to RNA. From RNA to Protein. Control of Gene Expression. Internal Organization of the Cell. Membrane Transport of Molecules. The Cell Cycle and Programmed Cell Death. The Mechanics of Cell Division. Mitosis and Meiosis. Patterns of Inheritance. Mendel’s experiments. Sex chromosomes and sex-linked inheritance. Human genetics. Human Genome Project. Stem Cells.

1) Alberts et al. L’Essenziale di Biologia Molecolare della Cellula . Zanichelli

2) Maraldi, Tacchetti et al. Biologia Citologia Medica Ediermes

3) De Leo et al. Biologia e Genetica Edises