Bio-physical and molecular basis

Module Applied biology

The purpose of the course is to provide students with a comprehensive understanding of the fundamental cellular processes that regulate the activities of living organisms. The main objectives include understanding cellular differentiation mechanisms, trait transmission, DNA replication, transcription, translation, and genetic information modification. By the end of the course, students should be able to apply this biological and molecular knowledge to comprehend how eukaryotic cells function under both normal and pathological conditions.

The course is structured as frontal lessons. However, if teaching needs to be conducted in a blended or remote mode, necessary adjustments may be introduced to ensure that the planned program outlined in the syllabus is still adhered to.

Knowledge of the key cellular processes. 

(important)

Structural and Functional Organization of Eukaryotic and Prokaryotic Cells. Principles and Molecular Mechanisms of Evolution. From Genotype to Phenotype. Phenotype and Environment. Biological and Molecular Mechanisms of Cell Differentiation. Nuclear and Organelle Genomes. Cell Proliferation. Chromatin and Chromosomes. DNA Replication. Biological Functions and Genome Expression. Classification and Structure of Eukaryotic, Prokaryotic, and Viral Genes. Transcription:  the synthesis and processing of RNA molecules. Genetic Code. Protein Synthesis. Genetic Mutations and Epigenetic Modifications. Cell Division. Genetic Inheritance in Humans. Mendelian Genetics. Cell Membranes. Cellular Organelles. Intracellular and Intercellular Molecular Trafficking. Signal Transduction. Differentiation and Apoptosis. Neoplastic Phenotype. Stem Cells.  

Reference book

1) Alberts et al. L’Essenziale di Biologia Molecolare della Cellula . Zanichelli

3) De Leo et al. Biologia e Genetica Edises

2) Maraldi, Tacchetti et al. Biologia Citologia Medica Ediermes

Oral exam. Elements to be evaluated: relevance of the answers, quality of their contents, ability to connect with other topics within the program, ability to report examples, quality of technical language, and overall expressive ability.

To guarantee equal opportunities and in compliance with current laws, students can request a meeting in order to plan any compensatory and/or dispensatory measure, according to the educational goals and specific needs. In this case, it is advisable to contact the CInAP (Centre for Active and Participated Integration - Services for Disabilities and/or SLD) professor of the Department where the Degree Course is included

Transcription, Structure and function of the plasma membrane, DNA replication, gametogenesis.