BIOLOGIA MOLECOLARE E BIOLOGIA MOLECOLARE AVANZATA M - ZModule BIOLOGIA MOLECOLARE
Academic Year 2022/2023 - Teacher: NUNZIO IRACIExpected Learning Outcomes
The course of Molecular Biology aims to provide the basis for the understanding of the physical, chemical and biological contexts in which molecules, reactions and metabolic pathways are framed; to highlight the relationships between structure and function of the main classes of macromolecules and the metabolic regulation at the molecular and cellular level. To stimulate the interest of the student, the various topics will be explained underlining the logical and consequential interconnections, highlighting the clinical aspects, introducing the experimental methods. At the end of the course the student will understand the structure-function relationships of the main biological molecules, the biochemical mechanisms essential for a correct metabolic function and the consequences of their alterations.
Course Structure
Lectures. Should teaching be carried out in mixed mode or remotely, it may be necessary to introduce changes with respect to previous statements, in line with the programme planned and outlined in the syllabus.
Learning assessment may also be carried out on line, should the conditions require it.
Information for students with disabilities and / or SLD: To guarantee equal opportunities and in compliance with the laws in force, interested students can ask for a personal interview in order to plan any compensatory and / or dispensatory measures, based on the teaching objectives and specifications needs. It is also possible to contact the CInAP contact person (Center for Active and Participatory Integration - Services for Disabilities and / or SLD) of the Department of Biomedical and Biotechonological Sciences.
Detailed Course Content
1 The structure of proteins, DNA and RNA
2 The organization of the prokaryotic and eukaryotic genome
3 Transcription in prokaryotes and eukaryotes
4 The regulation of transcription in prokaryotes
5 The maturation of RNA
6 Protein synthesis and the genetic code
7 The processing of proteins
8 DNA replication
9 The main molecular biology techniques
Textbook Information
Zlatanova & van Holde, Molecular Biology: Structure and Dynamics of Genomes and Proteomes
Course Planning
| Subjects | Text References | |
|---|---|---|
| 1 | La struttura di proteine, DNA ed RNA | Zlatanova & van Holde |
| 2 | L’organizzazione del genoma procariotico e eucariotico | Zlatanova & van Holde |
| 3 | La trascrizione nei procarioti e negli eucarioti | Zlatanova & van Holde |
| 4 | La regolazione della trascrizione nei procarioti | Zlatanova & van Holde |
| 5 | La maturazione dell’RNA | Zlatanova & van Holde |
| 6 | La sintesi proteica e il codice genetico | Zlatanova & van Holde |
| 7 | Il processamento delle proteine | Zlatanova & van Holde |
| 8 | La replicazione del DNA | Zlatanova & van Holde |
| 9 | Le principali tecniche di biologia molecolare | Zlatanova & van Holde |