CITOCHIMICA ED ISTOCHIMICA NEL DIFFERENZIAMENTO CELLULARE E TESSUTALE
Academic Year 2022/2023 - Teacher: MICHELINO DANIELE ANTONIO DI ROSAExpected Learning Outcomes
The aim of the discipline is to provide students with the main knowledge concerning the regulatory mechanisms that characterize the different cell lines during differentiation into specialized tissue components and the main cytochemical and histochemical methods applied to them.
Course Structure
Frontal lessons.
If the teaching is given in a mixed or remote mode, the necessary changes may be introduced with respect to what was previously stated, in order to comply with the program envisaged and reported in the syllabus.
Required Prerequisites
Attendance of Lessons
Obligation to attend
Detailed Course Content
Mechanisms of cell tissue differentiation with particular attention to the hematopoietic population - Immunological polarization - Stem cells -
- Main applied cytochemical and histochemical methods
- NERVOUS TISSUE: cell population and differentiation
-EPITHELIAL TISSUE: cell population and differentiation
- LYMPHOID TISSUE: cell population and differentiation
- BONE TISSUES: cell population and differentiation
- HEMOPOIETIC SYSTEM - MAIN HEMOPOIETIC ORGANS: cell population and differentiation
Textbook Information
HUMAN HISTOLOGY:
ELEMENTI DI ISTOLOGIA E CENNI DI EMBRIOLOGIA di S. Adamo, N. Bernerdini, C.Boitani, L. Bonsi, ……..… E. Ziparo - Piccin
Other teaching material: pdf documents uploaded on the STUDIUM digital platform, relating to the topics presented during the lectures.
Course Planning
| Subjects | Text References | |
|---|---|---|
| 1 | Surfacing epithelium: Generalities - Classification - Description of the different types of epithelium: simple squamous epithelium, simple cuboidal epithelium, simple columnar epithelium, stratified squamous epithelium, stratified cuboidal and stratified columnar epithelium, pseudostratified epithelium, transitional epithelium - Lateral surface specializations – Basal surface specializations – Apical surface specializations | |
| 2 | Glandular epithelium: Generalities - Exocrine glands: classification, structure and function - Endocrine glands: Hormones - Target cell - Hormone-receptor link - Classification - Structure and function of some endocrine glands: pituitary, thyroid, parathyroid, epiphysis, adrenal gland. | |
| 3 | CONNECTIVE TISSUES AND SPECIALIZED CONNECTIVE TISSUES: Connective tissue: Generalities and functions, cells, extracellular matrix, amorphous matrix, fibers - Structural and functional characteristics of the different types of connective tissue: Loose connective tissue, Dense connective tissue, Adipose tissue. | |
| 4 | Cartilage: Structural and functional characteristics, extracellular matrix, types of cartilage, histogenesis of cartilage, perichondrium. | |
| 5 | Bone tissue: Cells and extracellular matrix, bone lamellae and lamellar systems; compact and trabecular bone, periosteum and endosteum, ossification, metabolic functions of bone tissue. | |
| 6 | Blood: Generalities and functions - Plasma - Erythrocytes - Leukocytes: Neutrophils, Eosinophils, Basophils, Lymphocytes, Monocytes - Platelets. | |
| 7 | NERVOUS TISSUE: Generalities - Neuron: Shape and size, Cytoplasm, Cytoskeleton, Neural processes ( axon and dendrites), Axonal transport, Nerve fiber, Myelin sheath, Impulse conduction - Synapse - Neuroglia |
Learning Assessment
Learning Assessment Procedures
Oral examination
The oral examination consists of an interview in which questions will be asked that will focus on the different topics of the study program.
The test allows to verify:
i) the level of knowledge of human histology in physiological conditions of the organism.
ii) clarity of presentation.
iii) the property of medical-scientific language.
For the attribution of the final grade, the following parameters will be taken into account:
Grade 29-30 with honors: the student has a thorough knowledge of the topics discussed during the exam; he is able to promptly and correctly integrate and critically analyze the topics covered by the interview; he has excellent communication skills and masters medical-scientific language.
Grade 26-28: the student has a good knowledge of the topics discussed during the exam, he is able to integrate and analyze the topics covered by the interview in a critical and linear way and he presents the topics clearly using an appropriate medical-scientific language;
Grade 22-25: the student has a fair knowledge of the topics discussed during the exam, even if limited to the main topics; he manages to integrate and analyze in a critical but not always linear way the topics covered by the interview and he exposes the topics quite clearly with a discrete property of language;
Score 18-21: the student has minimal knowledge of the topics discussed during the exam, he has a modest ability to integrate and critically analyze the topics covered by the interview and he explains the topics in a sufficiently clear way although the language property is underdeveloped;
Failed exam: the student does not have the minimum required knowledge of the main teaching contents. The ability to use specific language is very little or absent and he is unable to independently apply the acquired knowledge.
Examples of frequently asked questions and / or exercises
1 What is the morphological organization of the heart muscle?
2 What is the classification of the exocrine glands?
3 What are the functions of leukocytes?
4 What shape do erythrocytes have and why?
5 Describe the cytological characteristics of the neuron
6 Describe the structural differences between cartilage and bone tissue
7 What is the myelin sheath?
8 What is the ultrastructural organization of the skeletal muscle fiber?